The article presents substantiation of the concept for construction of the Ergatic Airspace System for monitoring of the environment. The system includes multi-purpose manned and unmanned aerial vehicles, a land mobile system for monitoring of the stationary and mobile land objects, satellite navigation and communication systems (GLONASS, Gonets, Yamal, Arktika, RSCC Space Communication, lridium, Galileo), a station of ground mobile control of the monitoring system, a station of air control and remote control of the multi-purpose unmanned aerial vehicles for solving the problems of the environment protection. The principles were substantiated for complexation of the Ergatic Airspace System of monitoring on the basis of the manned and unmanned aerial vehicles, satellite navigation systems, mobile satellite communications and mobile system for monitoring of the stationary and mobile land objects. The developed layout sample of the unified land mobile station for control and diagnostics of the state of equipment for the multipurpose unmanned aerial vehicles allows to solve the following problems: autonomous automatic control of LUAV during environmental monitoring; remote command-leader control of LUAV groups in special flights; reference maneuvering in case of changing targets of monitoring; combined control, when LUAV groups go to the area of application autonomously under the program, while application of the target load is produced by the remote command control Complex use of GLONASS/GPS technologies and multifunctional satellite communications and data transmission systems Gonets-DIM, Yamal, Arktika, RSCC Space Communication, Iridium, and Galileo in the Ergatic Airspace System of monitoring provides effective solutions to the problems of monitoring and environment protection in the Russian Federation, CIS States and partner countries.